Laurence Lamant Selected Research

Anaplastic Large-Cell Lymphoma (Ki 1 Lymphoma)

1/2021	Whole Exome Sequencing reveals NOTCH1 mutations in anaplastic large cell lymphoma and points to Notch both as a key pathway and a potential therapeutic target.
1/2021	Minimal Residual Disease Monitoring Using a 3'ALK Universal Probe Assay in ALK-Positive Anaplastic Large-Cell Lymphoma: ddPCR, an Attractive Alternative Method to Real-Time Quantitative PCR.
1/2021	Should treatment of ALK-positive anaplastic large cell lymphoma be stratified according to minimal residual disease?
12/2020	ALK-transformed mature T lymphocytes restore early thymus progenitor features.
1/2019	Blockade of crizotinib-induced BCL2 elevation in ALK-positive anaplastic large cell lymphoma triggers autophagy associated with cell death.
1/2019	miR-497 suppresses cycle progression through an axis involving CDK6 in ALK-positive cells.
3/2018	Doxorubicin-induced loss of DNA topoisomerase II and DNMT1- dependent suppression of MiR-125b induces chemoresistance in ALK-positive cells.
1/2017	Long-term outcomes of adults with first-relapsed/refractory systemic anaplastic large-cell lymphoma in the pre-brentuximab vedotin era: A LYSA/SFGM-TC study.
1/2016	Anaplastic large cell lymphoma in paediatric and young adult patients.
10/2015	Targeting autophagy enhances the anti-tumoral action of crizotinib in ALK-positive anaplastic large cell lymphoma.

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Laurence Lamant Research Topics

Disease

28	Anaplastic Large-Cell Lymphoma (Ki 1 Lymphoma) 01/2021 - 08/2003
27	Neoplasms (Cancer) 01/2022 - 08/2004
18	Melanoma (Melanoma, Malignant) 06/2022 - 05/2003
11	Lymphoma (Lymphomas) 01/2022 - 05/2010
5	Genetic Translocation (Chromosomal Translocation) 01/2022 - 03/2008
4	Carcinogenesis 01/2019 - 10/2003
4	Non-Hodgkin Lymphoma (Lymphosarcoma) 12/2011 - 05/2006
3	Hyperpigmentation 02/2020 - 01/2008
3	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 09/2015 - 10/2003
3	Peripheral T-Cell Lymphoma (Lymphoma, T Cell, Peripheral) 11/2014 - 11/2012
3	T-Cell Lymphoma (Lymphoma, T Cell) 11/2012 - 05/2010
2	Neurofibrosarcoma (MPNST) 12/2018 - 12/2017
2	Neoplasm Metastasis (Metastasis) 01/2018 - 08/2008
2	Nevus (Nevi) 01/2018 - 01/2015
2	Disease Progression 01/2018 - 09/2009
2	Panniculitis 01/2017 - 08/2013
2	B-Cell Lymphoma (Lymphoma, B Cell) 09/2015 - 01/2014
2	Hypersensitivity (Allergy) 06/2015 - 01/2014
2	Chromosome Aberrations (Chromosome Abnormalities) 01/2015 - 08/2003
2	Cutaneous T-Cell Lymphoma (Lymphoma, T Cell, Cutaneous) 05/2010 - 01/2009
2	Netherton Syndrome 03/2010 - 10/2003
1	Peripheral Nervous System Diseases (PNS Diseases) 07/2022
1	Residual Neoplasm 01/2021
1	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL) 01/2020
1	Keratoacanthoma 12/2019
1	Mouth Neoplasms (Oral Cancer) 11/2017
1	Ichthyosis (Xeroderma) 03/2017
1	Deafness (Deaf Mutism) 03/2017
1	Keratosis 03/2017
1	Allergic Contact Dermatitis 03/2017
1	Angiolymphoid Hyperplasia with Eosinophilia 11/2015
1	Burkitt Lymphoma (Burkitt's Lymphoma) 09/2015
1	Hematologic Neoplasms (Hematological Malignancy) 11/2013

Drug/Important Bio-Agent (IBA)

22	Anaplastic Lymphoma KinaseIBA 01/2022 - 10/2003
12	Proteins (Proteins, Gene)FDA Link 01/2019 - 05/2003
6	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 01/2019 - 10/2003
5	MicroRNAs (MicroRNA)IBA 01/2019 - 06/2011
4	Messenger RNA (mRNA)IBA 06/2022 - 05/2010
4	Phosphotransferases (Kinase)IBA 01/2021 - 01/2012
4	DNA (Deoxyribonucleic Acid)IBA 01/2020 - 09/2007
4	Pyridinolcarbamate (P23)IBA 01/2019 - 08/2003
3	Tyrosine Kinase InhibitorsIBA 01/2019 - 09/2015
3	CrizotinibIBA 01/2019 - 09/2015
3	NucleophosminIBA 03/2018 - 08/2004
3	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2018 - 06/2015
3	Biomarkers (Surrogate Marker)IBA 01/2018 - 06/2015
3	AntibodiesIBA 01/2018 - 05/2003
3	VemurafenibIBA 01/2017 - 01/2012
3	Methotrexate (Mexate)FDA LinkGeneric 11/2015 - 02/2009
3	CytokinesIBA 05/2012 - 03/2010
2	Immune Checkpoint InhibitorsIBA 01/2020 - 12/2015
2	MART-1 AntigenIBA 12/2018 - 05/2003
2	Brentuximab VedotinIBA 01/2017 - 11/2014
2	T-Cell Antigen Receptors (T-Cell Receptor)IBA 01/2016 - 08/2013
2	Monoclonal AntibodiesIBA 01/2016 - 10/2003
2	Cytarabine (Cytosar-U)FDA LinkGeneric 09/2015 - 01/2015
2	Cyclophosphamide (Cytoxan)FDA LinkGeneric 09/2015 - 09/2009
2	Biological ProductsIBA 05/2014 - 02/2013
2	Tyrosine (L-Tyrosine)FDA Link 08/2013 - 08/2004
2	ChemokinesIBA 09/2012 - 05/2012
2	Vinblastine (Vinblastine Sulfate)FDA Link 09/2010 - 10/2009
2	Pharmaceutical PreparationsIBA 10/2009 - 01/2008
2	ClathrinIBA 10/2003 - 05/2003
1	B7-H1 AntigenIBA 06/2022
1	Cell Surface ReceptorsIBA 01/2022
1	Tacrolimus (Prograf)FDA LinkGeneric 02/2020
1	sphingosine kinaseIBA 01/2020
1	pembrolizumabIBA 12/2019
1	Oncogene Proteins (Oncogene Protein)IBA 01/2019
1	Monophenol Monooxygenase (Tyrosinase)IBA 12/2018
1	S100 Proteins (S 100 Protein)IBA 12/2018
1	Polycomb Repressive Complex 2IBA 12/2017
1	methyl 5-aminolevulinateIBA 03/2017
1	dabrafenibIBA 01/2017
1	cobimetinibIBA 01/2017
1	trametinibIBA 01/2017
1	Circulating MicroRNAIBA 01/2016
1	RNA (Ribonucleic Acid)IBA 01/2016
1	Alkylating AgentsIBA 09/2015
1	AnthracyclinesIBA 09/2015
1	Rituximab (Mabthera)FDA Link 09/2015
1	Transcription Factors (Transcription Factor)IBA 06/2015
1	Fluorouracil (Carac)FDA LinkGeneric 01/2015
1	Idarubicin (4 Demethoxydaunorubicin)FDA LinkGeneric 01/2015
1	Paclitaxel (Taxol)FDA LinkGeneric 01/2015
1	regorafenibIBA 01/2015
1	Bleomycin (Blenoxane)FDA LinkGeneric 01/2015
1	Histones (Histone)IBA 01/2014
1	Small Interfering RNA (siRNA)IBA 01/2014
1	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 11/2013
1	Cyclosporine (Ciclosporin)FDA LinkGeneric 08/2013
1	NestinIBA 02/2013

Therapy/Procedure

9	Therapeutics 07/2022 - 01/2008
8	Drug Therapy (Chemotherapy) 01/2021 - 09/2010
1	Lasers (Laser) 02/2020
1	Ligation 01/2020
1	Immunotherapy 01/2018
1	Combination Drug Therapy (Combination Chemotherapy) 01/2017
1	Radiotherapy 12/2015
1	Bone Marrow Transplantation (Transplantation, Bone Marrow) 11/2013